TMO vs XOM: Which Is the Better Buy?

Side-by-side comparison of Thermo Fisher Scientific Inc. and Exxon Mobil Corporation โ€” fair value, conviction, valuation metrics, and QuantHub research signals. Updated 2026-05-04.
Thermo Fisher Scientific Inc. ยท Healthcare
$462.60
+10.1% upside to fair value
Grade B
VS
Exxon Mobil Corporation ยท Energy
$154.46
-37.3% upside to fair value
Grade C
QuantHub Verdict
TMO has more upside to fair value (+10.1%). XOM trades at a lower forward P/E (23.2x). These are model outputs โ€” not personalized investment advice. See all research โ†’
Valuation & Fundamentals
Metric TMO XOM
Current Price $462.60 $154.46
Fair Value Estimate $509.20 $96.85
Upside to Fair Value +10.1% -37.3%
Market Cap $171.9B $642.0B
Forward P/E 25.1x 23.2x
EV / EBITDA 19.0x 10.3x
Price / Sales 3.8x 2.0x
Price / FCF 25.5x 27.2x
Revenue Growth YoY +6.2% -1.3%
Gross Margin 39.4% 21.7%
Operating Margin 17.8% 10.5%
Return on Equity 13.3% 11.0%
Dividend Yield 0% 0%
FCF Yield 3.92% 3.68%
Analyst Consensus Strong Buy Buy
Investment Thesis
TMO โ€” Thermo Fisher Scientific Inc.
Thermo Fisher Scientific Inc. operates in the healthcare sector, specializing in medical diagnostics and research tools across four main segments: Laboratory Products and Biopharma Services, Life Sciences Solutions, Analytical Instruments, and Specialty Diagnostics. The company demonstrates medium business quality with steady revenue growth of 6.2% and earnings growth of 9.6% in the most recent qโ€ฆ
XOM โ€” Exxon Mobil Corporation
Exxon Mobil Corporation operates as a global integrated oil and gas company with significant operations in upstream, energy products, chemical products, and specialty products segments. The company benefits from a highly experienced management team with decades of internal tenure, led by CEO Darren Woods. Despite strong cash flow generation and operational scale, Exxon is currently overvalued, trโ€ฆ
Accumulation Zones
Metric TMO XOM
Zone Low $381.90 $72.64
Zone High $432.82 $82.32
In Buy Zone? No No
โ† TMO Research    XOM Research โ†’    All Research