TMO vs WFC: Which Is the Better Buy?

Side-by-side comparison of Thermo Fisher Scientific Inc. and Wells Fargo & Company โ€” fair value, conviction, valuation metrics, and QuantHub research signals. Updated 2026-06-20.
Thermo Fisher Scientific Inc. ยท Healthcare
$464.61
+7.2% upside to fair value
Grade A High Quality
VS
Wells Fargo & Company ยท Financial Services
$82.21
+30.2% upside to fair value
Grade B
QuantHub Verdict
WFC has more upside to fair value (+30.2%). WFC trades at a lower forward P/E (12.0x). These are model outputs โ€” not personalized investment advice. See all research โ†’
Valuation & Fundamentals
Metric TMO WFC
Current Price $464.61 $82.21
Fair Value Estimate $498.27 $107.03
Upside to Fair Value +7.2% +30.2%
Market Cap $172.7B $251.6B
Forward P/E 25.2x 12.0x
EV / EBITDA 19.1x 15.8x
Price / Sales 3.8x 2.0x
Price / FCF 25.6x 213.4x
Revenue Growth YoY +6.2% +7.3%
Gross Margin 39.4% 64.5%
Operating Margin 17.8% 20.5%
Return on Equity 13.3% 12.0%
Dividend Yield 0% 0%
FCF Yield 3.91% 0.47%
Analyst Consensus Strong Buy Buy
Investment Thesis
TMO โ€” Thermo Fisher Scientific Inc.
Thermo Fisher Scientific is a leading healthcare company specializing in life science tools, diagnostics, and contract research and manufacturing services. It operates with a broad, multi-layered moat driven by scale, integration, and a long-tenured management team. The company exhibits solid fundamentals with a 13.3% ROE, 6.2% revenue growth, and 9.6% earnings growth in the most recent quarter. โ€ฆ
WFC โ€” Wells Fargo & Company
Wells Fargo & Company is a diversified financial services firm with a strong presence in consumer banking, commercial banking, corporate and investment banking, and wealth management. The company benefits from a large-scale moat in deposits, payments, and distribution, supported by a seasoned management team led by CEO Charles W. Scharf. Despite regulatory challenges and customer service issues tโ€ฆ
Accumulation Zones
Metric TMO WFC
Zone Low $373.70 $80.27
Zone High $423.53 $90.98
In Buy Zone? No Yes
โ† TMO Research    WFC Research โ†’    All Research