TMO vs VST: Which Is the Better Buy?
Side-by-side comparison of Thermo Fisher Scientific Inc. and Vistra Corp. — fair value, conviction, valuation metrics, and QuantHub research signals.
Updated 2026-08-06.
Thermo Fisher Scientific Inc. · Healthcare
$464.61
+7.2% upside to fair value
Grade A
High Quality
VS
Vistra Corp. · Utilities
$140.58
+20.9% upside to fair value
Med Conviction
Grade B
QuantHub Verdict
VST has more upside to fair value
(+20.9%).
VST trades at a lower forward P/E
(15.4x).
These are model outputs — not personalized investment advice.
See all research →
Valuation & Fundamentals
| Metric |
TMO |
VST |
| Current Price |
$464.61 |
$140.58 |
| Fair Value Estimate |
$498.27 |
$170.00 |
| Upside to Fair Value |
+7.2%
|
+20.9%
|
| Market Cap |
$172.7B |
$47.4B |
| Forward P/E |
25.2x
|
15.4x
|
| EV / EBITDA |
19.1x
|
9.3x
|
| Price / Sales |
3.8x
|
2.9x
|
| Price / FCF |
25.6x
|
42.5x
|
| Revenue Growth YoY |
+6.2%
|
+20.0%
|
| Gross Margin |
39.4%
|
12.7%
|
| Operating Margin |
17.8%
|
2.1%
|
| Return on Equity |
13.3%
|
35.0%
|
| Dividend Yield |
0% |
0.65% |
| FCF Yield |
3.91%
|
2.4%
|
| Analyst Consensus |
Strong Buy
|
Strong Buy
|
Investment Thesis
Thermo Fisher Scientific is a leading healthcare company specializing in life science tools, diagnostics, and contract research and manufacturing services. It operates with a broad, multi-layered moat driven by scale, integration, and a long-tenured management team. The company exhibits solid fundamentals with a 13.3% ROE, 6.2% revenue growth, and 9.6% earnings growth in the most recent quarter. …
Vistra is an integrated merchant power producer and retail electricity supplier with roughly 38,700 MW of generation across natural gas, nuclear, coal, solar and battery storage, plus a roughly 4.3 million customer retail book (TXU and affiliated brands) across 20 states. The 2024 Energy Harbor deal made it the second-largest nuclear operator in the US, and that nuclear and gas fleet is now centr…
Accumulation Zones
| Metric |
TMO |
VST |
| Zone Low |
$373.70 |
$128.00 |
| Zone High |
$423.53 |
$145.00 |
| In Buy Zone? |
No
|
Yes
|