PFE vs TSM: Which Is the Better Buy?
Side-by-side comparison of Pfizer Inc. and Taiwan Semiconductor Manufacturing Company Limited — fair value, conviction, valuation metrics, and QuantHub research signals.
Updated 2026-05-05.
Pfizer Inc. · Healthcare
$26.33
+28.6% upside to fair value
Grade B
VS
Taiwan Semiconductor Manufacturing Company Limited · Technology
$366.24
+45.0% upside to fair value
Grade C
High Quality
QuantHub Verdict
TSM has more upside to fair value
(+45.0%).
PFE trades at a lower forward P/E
(19.3x).
These are model outputs — not personalized investment advice.
See all research →
Valuation & Fundamentals
| Metric |
PFE |
TSM |
| Current Price |
$26.33 |
$366.24 |
| Fair Value Estimate |
$33.85 |
$531.05 |
| Upside to Fair Value |
+28.6%
|
+45.0%
|
| Market Cap |
$149.8B |
$1,899.5B |
| Forward P/E |
19.3x
|
27.2x
|
| EV / EBITDA |
12.9x
|
17.3x
|
| Price / Sales |
2.4x
|
12.8x
|
| Price / FCF |
16.5x
|
51.6x
|
| Revenue Growth YoY |
-1.2%
|
+36.5%
|
| Gross Margin |
70.3%
|
61.9%
|
| Operating Margin |
24.7%
|
53.2%
|
| Return on Equity |
8.7%
|
36.9%
|
| Dividend Yield |
0% |
0% |
| FCF Yield |
6.06%
|
1.94%
|
| Analyst Consensus |
Hold
|
Strong Buy
|
Investment Thesis
Pfizer Inc. is a leading global pharmaceutical company specializing in drug manufacturing with a strong presence in vaccines, oncology, and primary care. The company benefits from a seasoned leadership team under CEO Albert Bourla, who has driven a strategic transformation focusing on science-driven innovation and portfolio optimization. Despite a high gross margin of 70.3% and solid operating ma…
Taiwan Semiconductor Manufacturing Company Limited (TSMC) is the world's leading pure-play semiconductor foundry, commanding approximately 60% of the global advanced node foundry market. The company benefits from a durable competitive moat driven by its pioneering foundry model, massive scale, advanced manufacturing capabilities, and strong customer relationships with major technology firms. TSMC…
Accumulation Zones
| Metric |
PFE |
TSM |
| Zone Low |
$25.39 |
$398.29 |
| Zone High |
$28.77 |
$451.39 |
| In Buy Zone? |
Yes
|
Yes
|