PFE vs TMO: Which Is the Better Buy?
Side-by-side comparison of Pfizer Inc. and Thermo Fisher Scientific Inc. — fair value, conviction, valuation metrics, and QuantHub research signals.
Updated 2026-05-05.
Pfizer Inc. · Healthcare
$26.33
+35.4% upside to fair value
Grade B
VS
Thermo Fisher Scientific Inc. · Healthcare
$462.60
+10.1% upside to fair value
Grade B
QuantHub Verdict
PFE has more upside to fair value
(+35.4%).
PFE trades at a lower forward P/E
(19.3x).
These are model outputs — not personalized investment advice.
See all research →
Valuation & Fundamentals
| Metric |
PFE |
TMO |
| Current Price |
$26.33 |
$462.60 |
| Fair Value Estimate |
$35.65 |
$509.20 |
| Upside to Fair Value |
+35.4%
|
+10.1%
|
| Market Cap |
$149.8B |
$171.9B |
| Forward P/E |
19.3x
|
25.1x
|
| EV / EBITDA |
12.9x
|
19.0x
|
| Price / Sales |
2.4x
|
3.8x
|
| Price / FCF |
16.5x
|
25.5x
|
| Revenue Growth YoY |
-1.2%
|
+6.2%
|
| Gross Margin |
70.3%
|
39.4%
|
| Operating Margin |
24.7%
|
17.8%
|
| Return on Equity |
8.7%
|
13.3%
|
| Dividend Yield |
0% |
0% |
| FCF Yield |
6.06%
|
3.92%
|
| Analyst Consensus |
Hold
|
Strong Buy
|
Investment Thesis
Pfizer Inc. is a leading global pharmaceutical company specializing in drug manufacturing with a strong presence in vaccines, oncology, and primary care. The company benefits from a seasoned leadership team under CEO Albert Bourla, who has driven a strategic transformation focusing on science-driven innovation and portfolio optimization. Despite a high gross margin of 70.3% and solid operating ma…
Thermo Fisher Scientific Inc. operates in the healthcare sector, specializing in medical diagnostics and research tools across four main segments: Laboratory Products and Biopharma Services, Life Sciences Solutions, Analytical Instruments, and Specialty Diagnostics. The company demonstrates medium business quality with steady revenue growth of 6.2% and earnings growth of 9.6% in the most recent q…
Accumulation Zones
| Metric |
PFE |
TMO |
| Zone Low |
$26.74 |
$381.90 |
| Zone High |
$30.30 |
$432.82 |
| In Buy Zone? |
Yes
|
No
|