PFE vs PYPL: Which Is the Better Buy?
Side-by-side comparison of Pfizer Inc. and PayPal Holdings, Inc. — fair value, conviction, valuation metrics, and QuantHub research signals.
Updated 2026-09-18.
Pfizer Inc. · Healthcare
$27.64
+12.0% upside to fair value
Med Conviction
Grade B
VS
PayPal Holdings, Inc. · Financial Services
$52.71
+9.1% upside to fair value
Med Conviction
Grade B-
QuantHub Verdict
PFE has more upside to fair value
(+12.0%).
These are model outputs — not personalized investment advice.
See all research →
Valuation & Fundamentals
| Metric |
PFE |
PYPL |
| Current Price |
$27.64 |
$52.71 |
| Fair Value Estimate |
$30.94 |
$57.50 |
| Upside to Fair Value |
+12.0%
|
+9.1%
|
| Market Cap |
$157.5B |
$45.1B |
| Forward P/E |
—
|
—
|
| EV / EBITDA |
17.4x
|
6.8x
|
| Price / Sales |
2.5x
|
1.3x
|
| Price / FCF |
14.3x
|
7.2x
|
| Revenue Growth YoY |
+2.6%
|
+4.8%
|
| Gross Margin |
71.3%
|
45.8%
|
| Operating Margin |
25.1%
|
18.8%
|
| Return on Equity |
4.9%
|
24.4%
|
| Dividend Yield |
6.22% |
1.06% |
| FCF Yield |
6.97%
|
13.97%
|
| Analyst Consensus |
Hold
|
Hold
|
Investment Thesis
Pfizer is a global biopharmaceutical leader with a portfolio spanning cardiovascular, oncology, vaccines, immunology, and rare disease, anchored by Eliquis, the Prevnar family, Vyndaqel, Ibrance, Xtandi, Comirnaty, and Paxlovid, and supported by roughly 75,000 employees and a contract manufacturing division. Business quality is medium rather than high: TTM gross margin of 71.3% and TTM operating …
PayPal operates a global digital-payments platform spanning branded checkout, Venmo, Braintree merchant processing, credit products and fraud-risk infrastructure across approximately 200 markets. Business quality is medium: its two-sided network, trusted brand, broad merchant distribution and risk capabilities remain meaningful assets, but its highest-value branded-checkout franchise is under com…
Accumulation Zones
| Metric |
PFE |
PYPL |
| Zone Low |
$23.21 |
$43.12 |
| Zone High |
$26.30 |
$48.88 |
| In Buy Zone? |
No
|
No
|