PFE vs PLTR: Which Is the Better Buy?

Side-by-side comparison of Pfizer Inc. and Palantir Technologies Inc. โ€” fair value, conviction, valuation metrics, and QuantHub research signals. Updated 2026-09-26.
Pfizer Inc. ยท Healthcare
$27.64
+12.0% upside to fair value
Med Conviction Grade B
VS
Palantir Technologies Inc. ยท Technology
$189.67
+2.4% upside to fair value
Med Conviction Grade C High Quality
QuantHub Verdict
PFE has more upside to fair value (+12.0%). These are model outputs โ€” not personalized investment advice. See all research โ†’
Valuation & Fundamentals
Metric PFE PLTR
Current Price $27.64 $189.67
Fair Value Estimate $30.94 $194.30
Upside to Fair Value +12.0% +2.4%
Market Cap $157.5B $435.5B
Forward P/E โ€” โ€”
EV / EBITDA 17.4x 139.9x
Price / Sales 2.5x 70.7x
Price / FCF 14.3x 135.3x
Revenue Growth YoY +2.6% +92.8%
Gross Margin 71.3% 84.8%
Operating Margin 25.1% 42.8%
Return on Equity 4.9% 37.5%
Dividend Yield 6.22% 0%
FCF Yield 6.97% 0.74%
Analyst Consensus Hold Hold
Investment Thesis
PFE โ€” Pfizer Inc.
Pfizer is a global biopharmaceutical leader with a portfolio spanning cardiovascular, oncology, vaccines, immunology, and rare disease, anchored by Eliquis, the Prevnar family, Vyndaqel, Ibrance, Xtandi, Comirnaty, and Paxlovid, and supported by roughly 75,000 employees and a contract manufacturing division. Business quality is medium rather than high: TTM gross margin of 71.3% and TTM operating โ€ฆ
PLTR โ€” Palantir Technologies Inc.
Palantir Technologies Inc. is a software infrastructure company founded in 2003 and headquartered in Denver that builds and deploys Gotham for intelligence and defense workflows, Foundry as a central data operating system for enterprises, Apollo for software delivery across environments, and its Artificial Intelligence Platform (AIP) for unified access to open-source, self-hosted, and commercial โ€ฆ
Accumulation Zones
Metric PFE PLTR
Zone Low $23.21 $145.73
Zone High $26.30 $165.16
In Buy Zone? No No
โ† PFE Research    PLTR Research โ†’    All Research