LLY vs TSM: Which Is the Better Buy?

Side-by-side comparison of Eli Lilly and Company and Taiwan Semiconductor Manufacturing Company Limited โ€” fair value, conviction, valuation metrics, and QuantHub research signals. Updated 2026-05-01.
Eli Lilly and Company ยท Healthcare
$934.34
+17.6% upside to fair value
Grade B High Quality
VS
Taiwan Semiconductor Manufacturing Company Limited ยท Technology
$366.24
+45.0% upside to fair value
Grade C High Quality
QuantHub Verdict
TSM has more upside to fair value (+45.0%). TSM trades at a lower forward P/E (27.2x). These are model outputs โ€” not personalized investment advice. See all research โ†’
Valuation & Fundamentals
Metric LLY TSM
Current Price $934.34 $366.24
Fair Value Estimate $1,098.43 $531.05
Upside to Fair Value +17.6% +45.0%
Market Cap $882.8B $1,899.5B
Forward P/E 33.1x 27.2x
EV / EBITDA 27.9x 17.3x
Price / Sales 12.2x 12.8x
Price / FCF 65.0x 51.6x
Revenue Growth YoY +55.5% +36.5%
Gross Margin 82.7% 61.9%
Operating Margin 46.3% 53.2%
Return on Equity 101.3% 36.9%
Dividend Yield 0% 0%
FCF Yield 1.54% 1.94%
Analyst Consensus Strong Buy Strong Buy
Investment Thesis
LLY โ€” Eli Lilly and Company
Eli Lilly and Company is a leading global pharmaceutical firm with a dominant position in the diabetes and obesity markets, driven by its blockbuster GLP-1 drugs Mounjaro and Zepbound which generated $36.5 billion in FY2025. The company reported $65.2 billion in total revenue for 2025, making it the top pharma by revenue globally. It exhibits high business quality with a durable competitive moat โ€ฆ
TSM โ€” Taiwan Semiconductor Manufacturing Company Limited
Taiwan Semiconductor Manufacturing Company Limited (TSMC) is the world's leading pure-play semiconductor foundry, commanding approximately 60% of the global advanced node foundry market. The company benefits from a durable competitive moat driven by its pioneering foundry model, massive scale, advanced manufacturing capabilities, and strong customer relationships with major technology firms. TSMCโ€ฆ
Accumulation Zones
Metric LLY TSM
Zone Low $823.82 $398.29
Zone High $933.67 $451.39
In Buy Zone? No Yes
โ† LLY Research    TSM Research โ†’    All Research