LLY vs MA: Which Is the Better Buy?

Side-by-side comparison of Eli Lilly and Company and Mastercard Incorporated β€” fair value, conviction, valuation metrics, and QuantHub research signals. Updated 2026-05-13.
Eli Lilly and Company Β· Healthcare
$934.34
+17.6% upside to fair value
Grade B High Quality
VS
Mastercard Incorporated Β· Financial Services
$499.81
+5.0% upside to fair value
Grade B+ High Quality
QuantHub Verdict
LLY has more upside to fair value (+17.6%). MA trades at a lower forward P/E (28.6x). These are model outputs β€” not personalized investment advice. See all research β†’
Valuation & Fundamentals
Metric LLY MA
Current Price $934.34 $499.81
Fair Value Estimate $1,098.43 $525.00
Upside to Fair Value +17.6% +5.0%
Market Cap $882.8B $441.6B
Forward P/E 33.1x 28.6x
EV / EBITDA 27.9x 21.3x
Price / Sales 12.2x 13.0x
Price / FCF 65.0x 24.9x
Revenue Growth YoY +55.5% +15.8%
Gross Margin 82.7% 83.0%
Operating Margin 46.3% 59.4%
Return on Equity 101.3% 206.1%
Dividend Yield 0% 0.6%
FCF Yield 1.54% 4.01%
Analyst Consensus Strong Buy Strong Buy
Investment Thesis
LLY β€” Eli Lilly and Company
Eli Lilly and Company is a leading global pharmaceutical firm with a dominant position in the diabetes and obesity markets, driven by its blockbuster GLP-1 drugs Mounjaro and Zepbound which generated $36.5 billion in FY2025. The company reported $65.2 billion in total revenue for 2025, making it the top pharma by revenue globally. It exhibits high business quality with a durable competitive moat …
MA β€” Mastercard Incorporated
Mastercard is one of two global payment network duopolists alongside Visa, with structurally high margins (83% gross, 59% operating, 46% net), powerful network effects, and durable secular tailwinds from the ongoing cash-to-card and card-to-digital migration. Q1 2026 results reported April 30 showed revenue of $8.40 billion (+15.8% YoY) and EPS of $4.35 (+20.8% YoY), driven by continued cross-bor…
Accumulation Zones
Metric LLY MA
Zone Low $823.82 $393.75
Zone High $933.67 $446.25
In Buy Zone? No No
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