JNJ vs PFE: Which Is the Better Buy?

Side-by-side comparison of Johnson & Johnson and Pfizer Inc. โ€” fair value, conviction, valuation metrics, and QuantHub research signals. Updated 2026-05-05.
Johnson & Johnson ยท Healthcare
$230.69
+10.8% upside to fair value
Grade C High Quality
VS
Pfizer Inc. ยท Healthcare
$26.33
+28.6% upside to fair value
Grade B
QuantHub Verdict
PFE has more upside to fair value (+28.6%). PFE trades at a lower forward P/E (19.3x). These are model outputs โ€” not personalized investment advice. See all research โ†’
Valuation & Fundamentals
Metric JNJ PFE
Current Price $230.69 $26.33
Fair Value Estimate $255.61 $33.85
Upside to Fair Value +10.8% +28.6%
Market Cap $555.9B $149.8B
Forward P/E 26.8x 19.3x
EV / EBITDA 18.5x 12.9x
Price / Sales 5.8x 2.4x
Price / FCF 28.2x 16.5x
Revenue Growth YoY +9.9% -1.2%
Gross Margin 69.1% 70.3%
Operating Margin 26.9% 24.7%
Return on Equity 26.5% 8.7%
Dividend Yield 0% 0%
FCF Yield 3.54% 6.06%
Analyst Consensus Buy Hold
Investment Thesis
JNJ โ€” Johnson & Johnson
Johnson & Johnson is a leading healthcare company focused on pharmaceuticals and medical devices following its consumer health spin-off. The business quality is high due to its durable competitive moat, diversified portfolio, and strong management with deep institutional knowledge. Despite a 52.4% decline in earnings in the most recent quarter, revenue grew 9.9% year-over-year in the same period,โ€ฆ
PFE โ€” Pfizer Inc.
Pfizer Inc. is a leading global pharmaceutical company specializing in drug manufacturing with a strong presence in vaccines, oncology, and primary care. The company benefits from a seasoned leadership team under CEO Albert Bourla, who has driven a strategic transformation focusing on science-driven innovation and portfolio optimization. Despite a high gross margin of 70.3% and solid operating maโ€ฆ
Accumulation Zones
Metric JNJ PFE
Zone Low $191.71 $25.39
Zone High $217.27 $28.77
In Buy Zone? No Yes
โ† JNJ Research    PFE Research โ†’    All Research