JNJ vs LLY: Which Is the Better Buy?

Side-by-side comparison of Johnson & Johnson and Eli Lilly and Company β€” fair value, conviction, valuation metrics, and QuantHub research signals. Updated 2026-04-11.
Johnson & Johnson Β· Healthcare
$238.46
-11.8% upside to fair value
Med Conviction Grade C+
VS
Eli Lilly and Company Β· Healthcare
$939.47
+71.1% upside to fair value
High Conviction Grade A
QuantHub Verdict
LLY has more upside to fair value (+71.1%). JNJ trades at a lower forward P/E (20.2x). These are model outputs β€” not personalized investment advice. See all research β†’
Valuation & Fundamentals
Metric JNJ LLY
Current Price $238.46 $939.47
Fair Value Estimate $210.28 $1,607.00
Upside to Fair Value -11.8% +71.1%
Market Cap $574.7B $887.6B
Forward P/E 20.2x 27.4x
EV / EBITDA 13.3x 35.8x
Price / Sales 6.2x 14.8x
Price / FCF 29.4x 107.6x
Revenue Growth YoY +6.1% +44.7%
Gross Margin 72.8% 83.8%
Operating Margin 27.2% 45.6%
Return on Equity 32.87% 77.8%
Dividend Yield 2.18% 0.56%
FCF Yield 3.4% 0.93%
Analyst Consensus Moderate Buy Strong Buy
Investment Thesis
JNJ β€” Johnson & Johnson
Johnson & Johnson is a high-quality healthcare conglomerate focused exclusively on Innovative Medicine and MedTech following the Kenvue spin-off. The company delivered $94.2B in FY2025 revenue with 6% operational growth, generated $19.7B in free cash flow, and guided for $99.5-100.5B in 2026 operational sales (above consensus). However, at $238 the stock trades at a P/S of 6.15x, well above the 5…
LLY β€” Eli Lilly and Company
Eli Lilly remains the dominant GLP-1 franchise holder with Mounjaro and Zepbound generating $36.5B combined in 2025 on 45% total revenue growth to $65.2B. The company guided $80-83B for 2026, well above prior Street consensus, and launched Foundayo (oral GLP-1, FDA approved April 2026) with $1.5B pre-built inventory. At $939 the stock trades at 14.8x P/S, right at its 5-year median, and 27.4x for…
Accumulation Zones
Metric JNJ LLY
Zone Low $157.71 $1,205.00
Zone High $178.74 $1,366.00
In Buy Zone? No Yes
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