JNJ vs LLY: Which Is the Better Buy?

Side-by-side comparison of Johnson & Johnson and Eli Lilly and Company โ€” fair value, conviction, valuation metrics, and QuantHub research signals. Updated 2026-05-01.
Johnson & Johnson ยท Healthcare
$230.69
+10.8% upside to fair value
Grade C High Quality
VS
Eli Lilly and Company ยท Healthcare
$934.34
+17.6% upside to fair value
Grade B High Quality
QuantHub Verdict
LLY has more upside to fair value (+17.6%). JNJ trades at a lower forward P/E (26.8x). These are model outputs โ€” not personalized investment advice. See all research โ†’
Valuation & Fundamentals
Metric JNJ LLY
Current Price $230.69 $934.34
Fair Value Estimate $255.61 $1,098.43
Upside to Fair Value +10.8% +17.6%
Market Cap $555.9B $882.8B
Forward P/E 26.8x 33.1x
EV / EBITDA 18.5x 27.9x
Price / Sales 5.8x 12.2x
Price / FCF 28.2x 65.0x
Revenue Growth YoY +9.9% +55.5%
Gross Margin 69.1% 82.7%
Operating Margin 26.9% 46.3%
Return on Equity 26.5% 101.3%
Dividend Yield 0% 0%
FCF Yield 3.54% 1.54%
Analyst Consensus Buy Strong Buy
Investment Thesis
JNJ โ€” Johnson & Johnson
Johnson & Johnson is a leading healthcare company focused on pharmaceuticals and medical devices following its consumer health spin-off. The business quality is high due to its durable competitive moat, diversified portfolio, and strong management with deep institutional knowledge. Despite a 52.4% decline in earnings in the most recent quarter, revenue grew 9.9% year-over-year in the same period,โ€ฆ
LLY โ€” Eli Lilly and Company
Eli Lilly and Company is a leading global pharmaceutical firm with a dominant position in the diabetes and obesity markets, driven by its blockbuster GLP-1 drugs Mounjaro and Zepbound which generated $36.5 billion in FY2025. The company reported $65.2 billion in total revenue for 2025, making it the top pharma by revenue globally. It exhibits high business quality with a durable competitive moat โ€ฆ
Accumulation Zones
Metric JNJ LLY
Zone Low $191.71 $823.82
Zone High $217.27 $933.67
In Buy Zone? No No
โ† JNJ Research    LLY Research โ†’    All Research