ISRG vs TSM: Which Is the Better Buy?

Side-by-side comparison of Intuitive Surgical, Inc. and Taiwan Semiconductor Manufacturing Company Limited β€” fair value, conviction, valuation metrics, and QuantHub research signals. Updated 2026-07-17.
Intuitive Surgical, Inc. Β· Healthcare
$388.97
+45.0% upside to fair value
Grade B High Quality
VS
Taiwan Semiconductor Manufacturing Company Limited Β· Technology
$409.74
+45.0% upside to fair value
Grade C High Quality
QuantHub Verdict
TSM trades at a lower forward P/E (38.8x). These are model outputs β€” not personalized investment advice. See all research β†’
Valuation & Fundamentals
Metric ISRG TSM
Current Price $388.97 $409.74
Fair Value Estimate $564.01 $594.12
Upside to Fair Value +45.0% +45.0%
Market Cap $137.8B $2,125.1B
Forward P/E 46.5x 38.8x
EV / EBITDA 31.4x 17.6x
Price / Sales 13.0x 14.5x
Price / FCF 48.6x 58.4x
Revenue Growth YoY +23.0% +36.0%
Gross Margin 66.3% 61.9%
Operating Margin 30.5% 53.2%
Return on Equity 17.0% 36.9%
Dividend Yield 0% 0%
FCF Yield 2.06% 1.71%
Analyst Consensus Strong Buy Strong Buy
Investment Thesis
ISRG β€” Intuitive Surgical, Inc.
Intuitive Surgical, Inc. operates in the healthcare sector, specializing in medical devices with a strong focus on robotic-assisted surgery systems. The company demonstrates high business quality with a durable competitive moat supported by a 17.0% return on equity, robust gross margin of 66.3%, and solid operating margin of 30.5%. Revenue and earnings growth in the most recent quarter were impre…
TSM β€” Taiwan Semiconductor Manufacturing Company Limited
Taiwan Semiconductor Manufacturing Company Limited (TSM) is a leading semiconductor foundry specializing in advanced chip manufacturing technologies. The company exhibits high business quality with a durable competitive moat driven by cost advantages, intangible assets, and strong brand recognition. It demonstrates robust profitability with a net margin of 47.0% and a return on equity of 36.9%. R…
Accumulation Zones
Metric ISRG TSM
Zone Low $423.01 $445.59
Zone High $479.41 $505.00
In Buy Zone? Yes Yes
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