ISRG vs TMO: Which Is the Better Buy?

Side-by-side comparison of Intuitive Surgical, Inc. and Thermo Fisher Scientific Inc. β€” fair value, conviction, valuation metrics, and QuantHub research signals. Updated 2026-05-04.
Intuitive Surgical, Inc. Β· Healthcare
$451.29
+130.4% upside to fair value
Grade B High Quality
VS
Thermo Fisher Scientific Inc. Β· Healthcare
$462.60
+10.1% upside to fair value
Grade B
QuantHub Verdict
ISRG has more upside to fair value (+130.4%). TMO trades at a lower forward P/E (25.1x). These are model outputs β€” not personalized investment advice. See all research β†’
Valuation & Fundamentals
Metric ISRG TMO
Current Price $451.29 $462.60
Fair Value Estimate $1,039.74 $509.20
Upside to Fair Value +130.4% +10.1%
Market Cap $160.3B $171.9B
Forward P/E 53.8x 25.1x
EV / EBITDA 40.5x 19.0x
Price / Sales 15.2x 3.8x
Price / FCF 64.3x 25.5x
Revenue Growth YoY +23.0% +6.2%
Gross Margin 66.3% 39.4%
Operating Margin 30.5% 17.8%
Return on Equity 17.0% 13.3%
Dividend Yield 0% 0%
FCF Yield 1.55% 3.92%
Analyst Consensus Strong Buy Strong Buy
Investment Thesis
ISRG β€” Intuitive Surgical, Inc.
Intuitive Surgical, Inc. is a leading healthcare company specializing in robotic-assisted surgery through its flagship da Vinci system, which has established a durable competitive moat with approximately 10,000 systems installed globally and nearly 17 million procedures performed by the end of 2024. The company benefits from a high-quality business model characterized by 85% recurring revenue, st…
TMO β€” Thermo Fisher Scientific Inc.
Thermo Fisher Scientific Inc. operates in the healthcare sector, specializing in medical diagnostics and research tools across four main segments: Laboratory Products and Biopharma Services, Life Sciences Solutions, Analytical Instruments, and Specialty Diagnostics. The company demonstrates medium business quality with steady revenue growth of 6.2% and earnings growth of 9.6% in the most recent q…
Accumulation Zones
Metric ISRG TMO
Zone Low $779.81 $381.90
Zone High $883.78 $432.82
In Buy Zone? Yes No
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