ISRG vs PLTR: Which Is the Better Buy?

Side-by-side comparison of Intuitive Surgical, Inc. and Palantir Technologies Inc. β€” fair value, conviction, valuation metrics, and QuantHub research signals. Updated 2026-04-22.
Intuitive Surgical, Inc. Β· Healthcare
$451.29
+130.4% upside to fair value
Grade B High Quality
VS
Palantir Technologies Inc. Β· Technology
$142.76
-24.3% upside to fair value
Med Conviction Grade C
QuantHub Verdict
ISRG has more upside to fair value (+130.4%). ISRG trades at a lower forward P/E (53.8x). These are model outputs β€” not personalized investment advice. See all research β†’
Valuation & Fundamentals
Metric ISRG PLTR
Current Price $451.29 $142.76
Fair Value Estimate $1,039.74 $108.00
Upside to Fair Value +130.4% -24.3%
Market Cap $160.3B $327.1B
Forward P/E 53.8x 209.7x
EV / EBITDA 40.5x β€”
Price / Sales 15.2x 73.1x
Price / FCF 64.3x 155.7x
Revenue Growth YoY +23.0% +19.1%
Gross Margin 66.3% 82.4%
Operating Margin 30.5% 31.6%
Return on Equity 17.0% 25.7%
Dividend Yield 0% β€”
FCF Yield 1.55% 0.6%
Analyst Consensus Strong Buy Buy
Investment Thesis
ISRG β€” Intuitive Surgical, Inc.
Intuitive Surgical, Inc. is a leading healthcare company specializing in robotic-assisted surgery through its flagship da Vinci system, which has established a durable competitive moat with approximately 10,000 systems installed globally and nearly 17 million procedures performed by the end of 2024. The company benefits from a high-quality business model characterized by 85% recurring revenue, st…
PLTR β€” Palantir Technologies Inc.
Palantir Technologies develops data analytics and AI software platforms like Gotham and Foundry for government and commercial clients. The business excels with high margins (gross 82.4%, net 36.3%), accelerating growth (Q4 FY2025 revenue up 70% YoY to $1.41B, 2026 guidance $7.19B implying 61% growth), and strong moats in defense and enterprise AI, but trades expensively at 73x P/S versus 5-year m…
Accumulation Zones
Metric ISRG PLTR
Zone Low $779.81 $81.00
Zone High $883.78 $92.00
In Buy Zone? Yes No
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