ISRG vs MA: Which Is the Better Buy?
Side-by-side comparison of Intuitive Surgical, Inc. and Mastercard Incorporated β fair value, conviction, valuation metrics, and QuantHub research signals.
Updated 2026-05-13.
Intuitive Surgical, Inc. Β· Healthcare
$451.29
+45.0% upside to fair value
Grade B
High Quality
VS
Mastercard Incorporated Β· Financial Services
$499.81
+5.0% upside to fair value
Grade B+
High Quality
QuantHub Verdict
ISRG has more upside to fair value
(+45.0%).
MA trades at a lower forward P/E
(28.6x).
These are model outputs β not personalized investment advice.
See all research β
Valuation & Fundamentals
| Metric |
ISRG |
MA |
| Current Price |
$451.29 |
$499.81 |
| Fair Value Estimate |
$654.37 |
$525.00 |
| Upside to Fair Value |
+45.0%
|
+5.0%
|
| Market Cap |
$160.3B |
$441.6B |
| Forward P/E |
53.8x
|
28.6x
|
| EV / EBITDA |
40.5x
|
21.3x
|
| Price / Sales |
15.2x
|
13.0x
|
| Price / FCF |
64.3x
|
24.9x
|
| Revenue Growth YoY |
+23.0%
|
+15.8%
|
| Gross Margin |
66.3%
|
83.0%
|
| Operating Margin |
30.5%
|
59.4%
|
| Return on Equity |
17.0%
|
206.1%
|
| Dividend Yield |
0% |
0.6% |
| FCF Yield |
1.55%
|
4.01%
|
| Analyst Consensus |
Strong Buy
|
Strong Buy
|
Investment Thesis
Intuitive Surgical, Inc. is a leading healthcare company specializing in robotic-assisted surgery through its flagship da Vinci system, which has established a durable competitive moat with approximately 10,000 systems installed globally and nearly 17 million procedures performed by the end of 2024. The company benefits from a high-quality business model characterized by 85% recurring revenue, stβ¦
Mastercard is one of two global payment network duopolists alongside Visa, with structurally high margins (83% gross, 59% operating, 46% net), powerful network effects, and durable secular tailwinds from the ongoing cash-to-card and card-to-digital migration. Q1 2026 results reported April 30 showed revenue of $8.40 billion (+15.8% YoY) and EPS of $4.35 (+20.8% YoY), driven by continued cross-borβ¦
Accumulation Zones
| Metric |
ISRG |
MA |
| Zone Low |
$490.78 |
$393.75 |
| Zone High |
$556.21 |
$446.25 |
| In Buy Zone? |
Yes
|
No
|