ISRG vs MA: Which Is the Better Buy?

Side-by-side comparison of Intuitive Surgical, Inc. and Mastercard Incorporated โ€” fair value, conviction, valuation metrics, and QuantHub research signals. Updated 2026-09-25.
Intuitive Surgical, Inc. ยท Healthcare
$399.52
+22.4% upside to fair value
Med Conviction Grade B High Quality
VS
Mastercard Incorporated ยท Financial Services
$574.42
+25.0% upside to fair value
Med Conviction Grade A- High Quality
QuantHub Verdict
MA has more upside to fair value (+25.0%). These are model outputs โ€” not personalized investment advice. See all research โ†’
Valuation & Fundamentals
Metric ISRG MA
Current Price $399.52 $574.42
Fair Value Estimate $488.97 $718.00
Upside to Fair Value +22.4% +25.0%
Market Cap $141.1B $503.8B
Forward P/E โ€” โ€”
EV / EBITDA 30.7x 23.4x
Price / Sales 12.8x 14.4x
Price / FCF 44.0x 30.8x
Revenue Growth YoY +18.5% +14.1%
Gross Margin 66.7% 100%
Operating Margin 31.3% 59.8%
Return on Equity 17.8% 232.5%
Dividend Yield 0% 0.59%
FCF Yield 2.28% 3.25%
Analyst Consensus Strong Buy Strong Buy
Investment Thesis
ISRG โ€” Intuitive Surgical, Inc.
Intuitive Surgical develops, produces, and commercializes the da Vinci surgical system and the Ion endoluminal system, along with instruments, accessories, training, and digital solutions that drive a large installed-base and recurring-revenue model. Business quality is high: TTM gross margin of 66.7%, operating margin of 31.3%, net margin of 28.4%, ROE of 17.8%, and revenue growth of 18.5% with โ€ฆ
MA โ€” Mastercard Incorporated
Mastercard operates a global payments network that connects issuers, acquirers, merchants and consumers across more than 200 countries and territories, monetizing payment volumes, cross-border activity and higher-growth value-added services. Business quality is high because its two-sided network, trusted authorization-clearing-settlement infrastructure, brand, security capabilities and broad acceโ€ฆ
Accumulation Zones
Metric ISRG MA
Zone Low $366.73 $538.50
Zone High $415.62 $610.30
In Buy Zone? Yes Yes
โ† ISRG Research    MA Research โ†’    All Research