HD vs TMO: Which Is the Better Buy?
Side-by-side comparison of The Home Depot, Inc. and Thermo Fisher Scientific Inc. — fair value, conviction, valuation metrics, and QuantHub research signals.
Updated 2026-06-20.
The Home Depot, Inc. · Consumer Cyclical
$334.28
+34.7% upside to fair value
Grade A
High Quality
VS
Thermo Fisher Scientific Inc. · Healthcare
$464.61
+7.2% upside to fair value
Grade A
High Quality
QuantHub Verdict
HD has more upside to fair value
(+34.7%).
HD trades at a lower forward P/E
(23.7x).
These are model outputs — not personalized investment advice.
See all research →
Valuation & Fundamentals
| Metric |
HD |
TMO |
| Current Price |
$334.28 |
$464.61 |
| Fair Value Estimate |
$450.15 |
$498.27 |
| Upside to Fair Value |
+34.7%
|
+7.2%
|
| Market Cap |
$333.3B |
$172.7B |
| Forward P/E |
23.7x
|
25.2x
|
| EV / EBITDA |
16.1x
|
19.1x
|
| Price / Sales |
2.0x
|
3.8x
|
| Price / FCF |
23.3x
|
25.6x
|
| Revenue Growth YoY |
+4.8%
|
+6.2%
|
| Gross Margin |
33.1%
|
39.4%
|
| Operating Margin |
12.4%
|
17.8%
|
| Return on Equity |
113.3%
|
13.3%
|
| Dividend Yield |
0% |
0% |
| FCF Yield |
4.3%
|
3.91%
|
| Analyst Consensus |
Strong Buy
|
Strong Buy
|
Investment Thesis
The Home Depot, Inc. is the leading U.S. home improvement retailer with a dominant market share of approximately 47 to 50 percent, significantly ahead of Lowe's at 17 to 19 percent. The company benefits from a durable competitive moat driven by scale, a robust supply chain, and a pro-customer infrastructure. Its management team is composed of long-tenured insiders, including CEO Ted Decker who ha…
Thermo Fisher Scientific is a leading healthcare company specializing in life science tools, diagnostics, and contract research and manufacturing services. It operates with a broad, multi-layered moat driven by scale, integration, and a long-tenured management team. The company exhibits solid fundamentals with a 13.3% ROE, 6.2% revenue growth, and 9.6% earnings growth in the most recent quarter. …
Accumulation Zones
| Metric |
HD |
TMO |
| Zone Low |
$337.61 |
$373.70 |
| Zone High |
$382.63 |
$423.53 |
| In Buy Zone? |
Yes
|
No
|