HD vs PFE: Which Is the Better Buy?
Side-by-side comparison of The Home Depot, Inc. and Pfizer Inc. — fair value, conviction, valuation metrics, and QuantHub research signals.
Updated 2026-07-13.
The Home Depot, Inc. · Consumer Cyclical
$343.30
+34.6% upside to fair value
Grade A
High Quality
VS
Pfizer Inc. · Healthcare
$25.22
+2.8% upside to fair value
Grade B
QuantHub Verdict
HD has more upside to fair value
(+34.6%).
PFE trades at a lower forward P/E
(19.2x).
These are model outputs — not personalized investment advice.
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Valuation & Fundamentals
| Metric |
HD |
PFE |
| Current Price |
$343.30 |
$25.22 |
| Fair Value Estimate |
$462.14 |
$25.92 |
| Upside to Fair Value |
+34.6%
|
+2.8%
|
| Market Cap |
$342.3B |
$143.7B |
| Forward P/E |
24.3x
|
19.2x
|
| EV / EBITDA |
16.5x
|
12.3x
|
| Price / Sales |
2.0x
|
2.3x
|
| Price / FCF |
23.9x
|
15.2x
|
| Revenue Growth YoY |
+4.8%
|
+5.4%
|
| Gross Margin |
33.1%
|
69.3%
|
| Operating Margin |
12.4%
|
23.4%
|
| Return on Equity |
113.3%
|
8.4%
|
| Dividend Yield |
0% |
0% |
| FCF Yield |
4.18%
|
6.6%
|
| Analyst Consensus |
Buy
|
Hold
|
Investment Thesis
The Home Depot, Inc. operates as a leading home improvement retailer in the consumer cyclical sector, leveraging a strong brand and cost advantages to maintain a durable competitive moat. Despite a modest revenue growth of 4.8% and a decline in earnings by 4.2% in the most recent quarter, the company exhibits exceptional profitability metrics including a 113.3% return on equity and solid margins …
Pfizer Inc. is a leading global biopharmaceutical company with a diversified portfolio dominated by its Biopharma prescription segment, which accounts for over 90% of revenue. The company benefits from a substantial scale, a broad product portfolio including top-selling drugs like Eliquis, Prevnar, and Paxlovid, and a strong manufacturing footprint. However, Pfizer faces challenges from declining…
Accumulation Zones
| Metric |
HD |
PFE |
| Zone Low |
$346.61 |
$19.44 |
| Zone High |
$392.82 |
$22.03 |
| In Buy Zone? |
Yes
|
No
|