HD vs LLY: Which Is the Better Buy?

Side-by-side comparison of The Home Depot, Inc. and Eli Lilly and Company β€” fair value, conviction, valuation metrics, and QuantHub research signals. Updated 2026-04-11.
The Home Depot, Inc. Β· Consumer Cyclical
$337.34
+12.1% upside to fair value
Med Conviction Grade B
VS
Eli Lilly and Company Β· Healthcare
$939.47
+71.1% upside to fair value
High Conviction Grade A
QuantHub Verdict
LLY has more upside to fair value (+71.1%). HD trades at a lower forward P/E (23.0x). These are model outputs β€” not personalized investment advice. See all research β†’
Valuation & Fundamentals
Metric HD LLY
Current Price $337.34 $939.47
Fair Value Estimate $378.00 $1,607.00
Upside to Fair Value +12.1% +71.1%
Market Cap $336.0B $887.6B
Forward P/E 23.0x 27.4x
EV / EBITDA 18.1x 35.8x
Price / Sales 2.3x 14.8x
Price / FCF 29.7x 107.6x
Revenue Growth YoY +3.2% +44.7%
Gross Margin 33.3% 83.8%
Operating Margin 12.7% 45.6%
Return on Equity 110.5% 77.8%
Dividend Yield 2.44% 0.56%
FCF Yield 3.37% 0.93%
Analyst Consensus Buy Strong Buy
Investment Thesis
HD β€” The Home Depot, Inc.
Home Depot remains the world's largest home improvement retailer with 2,350+ stores, dominant 52% market share, and a rapidly growing Pro contractor segment bolstered by the SRS Distribution acquisition. The stock has declined 21% from its $427 high to $337, but now trades at 2.28x P/S, near the 5-year median of 2.31x, and 26.5x P/E which is above the 5-year median of 23.5x. EPS declined 4.6% in …
LLY β€” Eli Lilly and Company
Eli Lilly remains the dominant GLP-1 franchise holder with Mounjaro and Zepbound generating $36.5B combined in 2025 on 45% total revenue growth to $65.2B. The company guided $80-83B for 2026, well above prior Street consensus, and launched Foundayo (oral GLP-1, FDA approved April 2026) with $1.5B pre-built inventory. At $939 the stock trades at 14.8x P/S, right at its 5-year median, and 27.4x for…
Accumulation Zones
Metric HD LLY
Zone Low $285.00 $1,205.00
Zone High $320.00 $1,366.00
In Buy Zone? No Yes
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