HD vs LLY: Which Is the Better Buy?

Side-by-side comparison of The Home Depot, Inc. and Eli Lilly and Company โ€” fair value, conviction, valuation metrics, and QuantHub research signals. Updated 2026-05-20.
The Home Depot, Inc. ยท Consumer Cyclical
$302.44
+22.0% upside to fair value
Med Conviction Grade B+
VS
Eli Lilly and Company ยท Healthcare
$934.34
+17.6% upside to fair value
Grade B High Quality
QuantHub Verdict
HD has more upside to fair value (+22.0%). HD trades at a lower forward P/E (20.5x). These are model outputs โ€” not personalized investment advice. See all research โ†’
Valuation & Fundamentals
Metric HD LLY
Current Price $302.44 $934.34
Fair Value Estimate $369.00 $1,098.43
Upside to Fair Value +22.0% +17.6%
Market Cap $301.2B $882.8B
Forward P/E 20.5x 33.1x
EV / EBITDA 16.5x 27.9x
Price / Sales 2.0x 12.2x
Price / FCF 26.6x 65.0x
Revenue Growth YoY +4.8% +55.5%
Gross Margin 33.3% 82.7%
Operating Margin 12.7% 46.3%
Return on Equity 110.5% 101.3%
Dividend Yield 2.72% 0%
FCF Yield 3.75% 1.54%
Analyst Consensus Buy Strong Buy
Investment Thesis
HD โ€” The Home Depot, Inc.
Home Depot remains the world's largest home improvement retailer with 2,350+ stores, dominant 52% market share, and an expanding Pro contractor segment bolstered by the SRS Distribution acquisition. Q1 FY2026 results released May 19 beat both the top and bottom line, with revenue of $41.77B up 4.8% year over year and adjusted EPS of $3.43 versus the $3.41 consensus. Comp sales grew only 0.6% howeโ€ฆ
LLY โ€” Eli Lilly and Company
Eli Lilly and Company is a leading global pharmaceutical firm with a dominant position in the diabetes and obesity markets, driven by its blockbuster GLP-1 drugs Mounjaro and Zepbound which generated $36.5 billion in FY2025. The company reported $65.2 billion in total revenue for 2025, making it the top pharma by revenue globally. It exhibits high business quality with a durable competitive moat โ€ฆ
Accumulation Zones
Metric HD LLY
Zone Low $276.75 $823.82
Zone High $313.65 $933.67
In Buy Zone? Yes No
โ† HD Research    LLY Research โ†’    All Research