HD vs ISRG: Which Is the Better Buy?

Side-by-side comparison of The Home Depot, Inc. and Intuitive Surgical, Inc. β€” fair value, conviction, valuation metrics, and QuantHub research signals. Updated 2026-04-22.
The Home Depot, Inc. Β· Consumer Cyclical
$337.34
+12.1% upside to fair value
Med Conviction Grade B
VS
Intuitive Surgical, Inc. Β· Healthcare
$451.29
+130.4% upside to fair value
Grade B High Quality
QuantHub Verdict
ISRG has more upside to fair value (+130.4%). HD trades at a lower forward P/E (23.0x). These are model outputs β€” not personalized investment advice. See all research β†’
Valuation & Fundamentals
Metric HD ISRG
Current Price $337.34 $451.29
Fair Value Estimate $378.00 $1,039.74
Upside to Fair Value +12.1% +130.4%
Market Cap $336.0B $160.3B
Forward P/E 23.0x 53.8x
EV / EBITDA 18.1x 40.5x
Price / Sales 2.3x 15.2x
Price / FCF 29.7x 64.3x
Revenue Growth YoY +3.2% +23.0%
Gross Margin 33.3% 66.3%
Operating Margin 12.7% 30.5%
Return on Equity 110.5% 17.0%
Dividend Yield 2.44% 0%
FCF Yield 3.37% 1.55%
Analyst Consensus Buy Strong Buy
Investment Thesis
HD β€” The Home Depot, Inc.
Home Depot remains the world's largest home improvement retailer with 2,350+ stores, dominant 52% market share, and a rapidly growing Pro contractor segment bolstered by the SRS Distribution acquisition. The stock has declined 21% from its $427 high to $337, but now trades at 2.28x P/S, near the 5-year median of 2.31x, and 26.5x P/E which is above the 5-year median of 23.5x. EPS declined 4.6% in …
ISRG β€” Intuitive Surgical, Inc.
Intuitive Surgical, Inc. is a leading healthcare company specializing in robotic-assisted surgery through its flagship da Vinci system, which has established a durable competitive moat with approximately 10,000 systems installed globally and nearly 17 million procedures performed by the end of 2024. The company benefits from a high-quality business model characterized by 85% recurring revenue, st…
Accumulation Zones
Metric HD ISRG
Zone Low $285.00 $779.81
Zone High $320.00 $883.78
In Buy Zone? No Yes
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