DHR vs ISRG: Which Is the Better Buy?
Side-by-side comparison of Danaher Corporation and Intuitive Surgical, Inc. — fair value, conviction, valuation metrics, and QuantHub research signals.
Updated 2026-09-25.
Danaher Corporation · Healthcare
$221.12
+29.6% upside to fair value
Med Conviction
Grade B
High Quality
VS
Intuitive Surgical, Inc. · Healthcare
$399.52
+22.4% upside to fair value
Med Conviction
Grade B
High Quality
QuantHub Verdict
DHR has more upside to fair value
(+29.6%).
These are model outputs — not personalized investment advice.
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Valuation & Fundamentals
| Metric |
DHR |
ISRG |
| Current Price |
$221.12 |
$399.52 |
| Fair Value Estimate |
$286.52 |
$488.97 |
| Upside to Fair Value |
+29.6%
|
+22.4%
|
| Market Cap |
$155.4B |
$141.1B |
| Forward P/E |
—
|
—
|
| EV / EBITDA |
24.8x
|
30.7x
|
| Price / Sales |
6.2x
|
12.8x
|
| Price / FCF |
28.5x
|
44.0x
|
| Revenue Growth YoY |
+5.5%
|
+18.5%
|
| Gross Margin |
58.5%
|
66.7%
|
| Operating Margin |
20.4%
|
31.3%
|
| Return on Equity |
7.7%
|
17.8%
|
| Dividend Yield |
0.65% |
0% |
| FCF Yield |
3.51%
|
2.28%
|
| Analyst Consensus |
Strong Buy
|
Strong Buy
|
Investment Thesis
Danaher is a diversified life-sciences and diagnostics platform spanning three segments: Life Sciences (mass spectrometers, flow cytometry, genomics, bioprocess technologies), Diagnostics (chemistry, immunoassay, microbiology, hematology, molecular and pathology systems), and Environmental & Applied Solutions (water quality and product-identification instrumentation). The business quality is high…
Intuitive Surgical develops, produces, and commercializes the da Vinci surgical system and the Ion endoluminal system, along with instruments, accessories, training, and digital solutions that drive a large installed-base and recurring-revenue model. Business quality is high: TTM gross margin of 66.7%, operating margin of 31.3%, net margin of 28.4%, ROE of 17.8%, and revenue growth of 18.5% with …
Accumulation Zones
| Metric |
DHR |
ISRG |
| Zone Low |
$214.89 |
$366.73 |
| Zone High |
$243.54 |
$415.62 |
| In Buy Zone? |
Yes
|
Yes
|