DHR vs ISRG: Which Is the Better Buy?

Side-by-side comparison of Danaher Corporation and Intuitive Surgical, Inc. โ€” fair value, conviction, valuation metrics, and QuantHub research signals. Updated 2026-06-20.
Danaher Corporation ยท Healthcare
$177.17
+8.9% upside to fair value
Grade B High Quality
VS
Intuitive Surgical, Inc. ยท Healthcare
$406.78
+45.0% upside to fair value
Grade B High Quality
QuantHub Verdict
ISRG has more upside to fair value (+45.0%). DHR trades at a lower forward P/E (34.1x). These are model outputs โ€” not personalized investment advice. See all research โ†’
Valuation & Fundamentals
Metric DHR ISRG
Current Price $177.17 $406.78
Fair Value Estimate $192.90 $589.83
Upside to Fair Value +8.9% +45.0%
Market Cap $125.4B $144.1B
Forward P/E 34.1x 48.6x
EV / EBITDA 20.8x 32.9x
Price / Sales 5.1x 13.6x
Price / FCF 23.7x 50.8x
Revenue Growth YoY +3.7% +23.0%
Gross Margin 60.7% 66.3%
Operating Margin 21.0% 30.5%
Return on Equity 7.1% 17.0%
Dividend Yield 0% 0%
FCF Yield 4.22% 1.97%
Analyst Consensus Strong Buy Strong Buy
Investment Thesis
DHR โ€” Danaher Corporation
Danaher Corporation operates in the healthcare sector, specializing in medical diagnostics and research tools through three balanced platforms: Biotechnology, Life Sciences, and Diagnostics. The company benefits from a durable competitive moat supported by the Danaher Business System, disciplined capital allocation, and a platform-centric organizational structure. Despite modest revenue growth ofโ€ฆ
ISRG โ€” Intuitive Surgical, Inc.
Intuitive Surgical is a leading healthcare company specializing in robotic surgical systems, instruments, and accessories with a very wide competitive moat supported by over 80% global market share in installed systems and procedures. The company benefits from high recurring revenue streams driven by procedure volume and installed base utilization, with instruments and accessories generating $6.0โ€ฆ
Accumulation Zones
Metric DHR ISRG
Zone Low $144.68 $442.37
Zone High $163.97 $501.36
In Buy Zone? No Yes
โ† DHR Research    ISRG Research โ†’    All Research