CRM vs PFE: Which Is the Better Buy?

Side-by-side comparison of Salesforce, Inc. and Pfizer Inc. โ€” fair value, conviction, valuation metrics, and QuantHub research signals. Updated 2026-04-16.
Salesforce, Inc. ยท Technology
$181.22
+161.6% upside to fair value
High Conviction Grade A-
VS
Pfizer Inc. ยท Healthcare
$26.91
+30.1% upside to fair value
Med Conviction Grade B+
QuantHub Verdict
CRM has more upside to fair value (+161.6%). PFE trades at a lower forward P/E (9.5x). These are model outputs โ€” not personalized investment advice. See all research โ†’
Valuation & Fundamentals
Metric CRM PFE
Current Price $181.22 $26.91
Fair Value Estimate $474.00 $35.00
Upside to Fair Value +161.6% +30.1%
Market Cap $169.8B $153.0B
Forward P/E 22.7x 9.5x
EV / EBITDA โ€” 13.8x
Price / Sales 4.1x 2.4x
Price / FCF 11.8x 16.8x
Revenue Growth YoY +9.2% -1.6%
Gross Margin 77.7% 70.3%
Operating Margin 21.5% 24.7%
Return on Equity 12.4% 9.0%
Dividend Yield โ€” 6.4%
FCF Yield 8.5% 5.9%
Analyst Consensus Strong Buy Hold
Investment Thesis
CRM โ€” Salesforce, Inc.
Salesforce is the leading global provider of CRM software, offering a strong competitive moat through market dominance and high switching costs, complemented by acquisitions like Slack and Tableau, with excellent margins above 77% gross and robust free cash flow of $15.16 per share. Despite decelerating revenue growth at 9.2% YoY and negative earnings growth of -6.9%, the business remains high-quโ€ฆ
PFE โ€” Pfizer Inc.
Pfizer remains the world's largest traditional pharmaceutical company by non-COVID revenue, generating $62.6B in 2025 sales across oncology, cardiovascular, immunology, and vaccines. The stock trades at a P/S of 2.44x, still well below the 5-year median of 3.10x, driven by post-COVID revenue normalization, a $17-18B patent cliff spanning 2026-2028, and $61.6B in acquisition-related debt from Seagโ€ฆ
Accumulation Zones
Metric CRM PFE
Zone Low $356.00 $25.00
Zone High $403.00 $29.00
In Buy Zone? Yes Yes
โ† CRM Research    PFE Research โ†’    All Research