COST vs TMO: Which Is the Better Buy?

Side-by-side comparison of Costco Wholesale Corporation and Thermo Fisher Scientific Inc. β€” fair value, conviction, valuation metrics, and QuantHub research signals. Updated 2026-05-04.
Costco Wholesale Corporation Β· Consumer Defensive
$999.89
-19.1% upside to fair value
Grade D High Quality
VS
Thermo Fisher Scientific Inc. Β· Healthcare
$462.60
+10.1% upside to fair value
Grade B
QuantHub Verdict
TMO has more upside to fair value (+10.1%). TMO trades at a lower forward P/E (25.1x). These are model outputs β€” not personalized investment advice. See all research β†’
Valuation & Fundamentals
Metric COST TMO
Current Price $999.89 $462.60
Fair Value Estimate $808.71 $509.20
Upside to Fair Value -19.1% +10.1%
Market Cap $443.6B $171.9B
Forward P/E 51.9x 25.1x
EV / EBITDA 30.9x 19.0x
Price / Sales 1.6x 3.8x
Price / FCF 48.8x 25.5x
Revenue Growth YoY +9.2% +6.2%
Gross Margin 12.9% 39.4%
Operating Margin 3.8% 17.8%
Return on Equity 28.8% 13.3%
Dividend Yield 0% 0%
FCF Yield 2.05% 3.92%
Analyst Consensus Buy Strong Buy
Investment Thesis
COST β€” Costco Wholesale Corporation
Costco Wholesale Corporation operates a global membership-based warehouse club model that leverages scale, low costs, and superior employee retention to deliver consistent revenue and earnings growth. The company reported $269.9 billion in net sales for fiscal 2025 with an 8% year-over-year increase, driven by strong segments in Foods and Sundries and membership fees exceeding $5.65 billion in th…
TMO β€” Thermo Fisher Scientific Inc.
Thermo Fisher Scientific Inc. operates in the healthcare sector, specializing in medical diagnostics and research tools across four main segments: Laboratory Products and Biopharma Services, Life Sciences Solutions, Analytical Instruments, and Specialty Diagnostics. The company demonstrates medium business quality with steady revenue growth of 6.2% and earnings growth of 9.6% in the most recent q…
Accumulation Zones
Metric COST TMO
Zone Low $606.53 $381.90
Zone High $687.40 $432.82
In Buy Zone? No No
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