ASML vs TMO: Which Is the Better Buy?
Side-by-side comparison of ASML Holding N.V. and Thermo Fisher Scientific Inc. — fair value, conviction, valuation metrics, and QuantHub research signals.
Updated 2026-09-24.
ASML Holding N.V. · Technology
$1,744.61
-0.7% upside to fair value
Med Conviction
Grade C
High Quality
VS
Thermo Fisher Scientific Inc. · Healthcare
$658.32
+31.1% upside to fair value
Med Conviction
Grade B
High Quality
QuantHub Verdict
TMO has more upside to fair value
(+31.1%).
These are model outputs — not personalized investment advice.
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Valuation & Fundamentals
| Metric |
ASML |
TMO |
| Current Price |
$1,744.61 |
$658.32 |
| Fair Value Estimate |
$1,732.49 |
$863.34 |
| Upside to Fair Value |
-0.7%
|
+31.1%
|
| Market Cap |
$672.4B |
$244.7B |
| Forward P/E |
—
|
—
|
| EV / EBITDA |
42.0x
|
25.9x
|
| Price / Sales |
19.0x
|
5.3x
|
| Price / FCF |
67.2x
|
33.4x
|
| Revenue Growth YoY |
+21.3%
|
+10.5%
|
| Gross Margin |
52.7%
|
40.4%
|
| Operating Margin |
35.4%
|
17.7%
|
| Return on Equity |
52.4%
|
13.4%
|
| Dividend Yield |
0.51% |
0.28% |
| FCF Yield |
1.49%
|
3.0%
|
| Analyst Consensus |
Buy
|
Strong Buy
|
Investment Thesis
ASML Holding N.V. is the Dutch semiconductor equipment maker that supplies lithography, metrology, and inspection systems, including the extreme ultraviolet (EUV) machines required to pattern the most advanced logic and memory chips, and it holds what current coverage describes as a near-monopoly on those EUV tools. The business quality is genuinely high: TTM gross margin of 52.7%, TTM operating …
Thermo Fisher Scientific is a global life-sciences and laboratory-services platform spanning Life Sciences Solutions, Analytical Instruments, Specialty Diagnostics, and Laboratory Products and Biopharma Services, with recognized brands including Thermo Scientific, Applied Biosystems, Invitrogen, Fisher Scientific, Patheon, and PPD, serving pharmaceutical, biotech, clinical, academic, and governme…
Accumulation Zones
| Metric |
ASML |
TMO |
| Zone Low |
$1,299.37 |
$647.50 |
| Zone High |
$1,472.62 |
$733.84 |
| In Buy Zone? |
No
|
Yes
|