ASML vs TMO: Which Is the Better Buy?
Side-by-side comparison of ASML Holding N.V. and Thermo Fisher Scientific Inc. — fair value, conviction, valuation metrics, and QuantHub research signals.
Updated 2026-05-04.
ASML Holding N.V. · Technology
$1,458.97
+65.1% upside to fair value
Grade B
High Quality
VS
Thermo Fisher Scientific Inc. · Healthcare
$462.60
+10.1% upside to fair value
Grade B
QuantHub Verdict
ASML has more upside to fair value
(+65.1%).
TMO trades at a lower forward P/E
(25.1x).
These are model outputs — not personalized investment advice.
See all research →
Valuation & Fundamentals
| Metric |
ASML |
TMO |
| Current Price |
$1,458.97 |
$462.60 |
| Fair Value Estimate |
$2,408.73 |
$509.20 |
| Upside to Fair Value |
+65.1%
|
+10.1%
|
| Market Cap |
$562.3B |
$171.9B |
| Forward P/E |
48.3x
|
25.1x
|
| EV / EBITDA |
37.6x
|
19.0x
|
| Price / Sales |
14.4x
|
3.8x
|
| Price / FCF |
54.4x
|
25.5x
|
| Revenue Growth YoY |
+13.2%
|
+6.2%
|
| Gross Margin |
52.6%
|
39.4%
|
| Operating Margin |
34.8%
|
17.8%
|
| Return on Equity |
52.0%
|
13.3%
|
| Dividend Yield |
0% |
0% |
| FCF Yield |
1.84%
|
3.92%
|
| Analyst Consensus |
Strong Buy
|
Strong Buy
|
Investment Thesis
ASML Holding N.V. is a leading technology company specializing in semiconductor manufacturing equipment, particularly extreme ultraviolet lithography machines which hold a near-monopoly position. The company benefits from a durable competitive moat driven by its technological leadership, high barriers to entry, and strong demand from semiconductor manufacturers globally, especially in China. Desp…
Thermo Fisher Scientific Inc. operates in the healthcare sector, specializing in medical diagnostics and research tools across four main segments: Laboratory Products and Biopharma Services, Life Sciences Solutions, Analytical Instruments, and Specialty Diagnostics. The company demonstrates medium business quality with steady revenue growth of 6.2% and earnings growth of 9.6% in the most recent q…
Accumulation Zones
| Metric |
ASML |
TMO |
| Zone Low |
$1,806.55 |
$381.90 |
| Zone High |
$2,047.42 |
$432.82 |
| In Buy Zone? |
Yes
|
No
|