ASML vs PFE: Which Is the Better Buy?
Side-by-side comparison of ASML Holding N.V. and Pfizer Inc. — fair value, conviction, valuation metrics, and QuantHub research signals.
Updated 2026-04-22.
ASML Holding N.V. · Technology
$1,458.97
+65.1% upside to fair value
Grade B
High Quality
VS
Pfizer Inc. · Healthcare
$26.91
+30.1% upside to fair value
Med Conviction
Grade B+
QuantHub Verdict
ASML has more upside to fair value
(+65.1%).
PFE trades at a lower forward P/E
(9.5x).
These are model outputs — not personalized investment advice.
See all research →
Valuation & Fundamentals
| Metric |
ASML |
PFE |
| Current Price |
$1,458.97 |
$26.91 |
| Fair Value Estimate |
$2,408.73 |
$35.00 |
| Upside to Fair Value |
+65.1%
|
+30.1%
|
| Market Cap |
$562.3B |
$153.0B |
| Forward P/E |
48.3x
|
9.5x
|
| EV / EBITDA |
37.6x
|
13.8x
|
| Price / Sales |
14.4x
|
2.4x
|
| Price / FCF |
54.4x
|
16.8x
|
| Revenue Growth YoY |
+13.2%
|
-1.6%
|
| Gross Margin |
52.6%
|
70.3%
|
| Operating Margin |
34.8%
|
24.7%
|
| Return on Equity |
52.0%
|
9.0%
|
| Dividend Yield |
0% |
6.4% |
| FCF Yield |
1.84%
|
5.9%
|
| Analyst Consensus |
Strong Buy
|
Hold
|
Investment Thesis
ASML Holding N.V. is a leading technology company specializing in semiconductor manufacturing equipment, particularly extreme ultraviolet lithography machines which hold a near-monopoly position. The company benefits from a durable competitive moat driven by its technological leadership, high barriers to entry, and strong demand from semiconductor manufacturers globally, especially in China. Desp…
Pfizer remains the world's largest traditional pharmaceutical company by non-COVID revenue, generating $62.6B in 2025 sales across oncology, cardiovascular, immunology, and vaccines. The stock trades at a P/S of 2.44x, still well below the 5-year median of 3.10x, driven by post-COVID revenue normalization, a $17-18B patent cliff spanning 2026-2028, and $61.6B in acquisition-related debt from Seag…
Accumulation Zones
| Metric |
ASML |
PFE |
| Zone Low |
$1,806.55 |
$25.00 |
| Zone High |
$2,047.42 |
$29.00 |
| In Buy Zone? |
Yes
|
Yes
|