ASML vs PFE: Which Is the Better Buy?

Side-by-side comparison of ASML Holding N.V. and Pfizer Inc. β€” fair value, conviction, valuation metrics, and QuantHub research signals. Updated 2026-05-05.
ASML Holding N.V. Β· Technology
$1,458.97
+45.0% upside to fair value
Grade B High Quality
VS
Pfizer Inc. Β· Healthcare
$26.33
+28.6% upside to fair value
Grade B
QuantHub Verdict
ASML has more upside to fair value (+45.0%). PFE trades at a lower forward P/E (19.3x). These are model outputs β€” not personalized investment advice. See all research β†’
Valuation & Fundamentals
Metric ASML PFE
Current Price $1,458.97 $26.33
Fair Value Estimate $2,115.51 $33.85
Upside to Fair Value +45.0% +28.6%
Market Cap $562.3B $149.8B
Forward P/E 48.3x 19.3x
EV / EBITDA 37.6x 12.9x
Price / Sales 14.4x 2.4x
Price / FCF 54.4x 16.5x
Revenue Growth YoY +13.2% -1.2%
Gross Margin 52.6% 70.3%
Operating Margin 34.8% 24.7%
Return on Equity 52.0% 8.7%
Dividend Yield 0% 0%
FCF Yield 1.84% 6.06%
Analyst Consensus Strong Buy Hold
Investment Thesis
ASML β€” ASML Holding N.V.
ASML Holding N.V. is a leading technology company specializing in semiconductor manufacturing equipment, particularly extreme ultraviolet lithography machines which hold a near-monopoly position. The company benefits from a durable competitive moat driven by its technological leadership, high barriers to entry, and strong demand from semiconductor manufacturers globally, especially in China. Desp…
PFE β€” Pfizer Inc.
Pfizer Inc. is a leading global pharmaceutical company specializing in drug manufacturing with a strong presence in vaccines, oncology, and primary care. The company benefits from a seasoned leadership team under CEO Albert Bourla, who has driven a strategic transformation focusing on science-driven innovation and portfolio optimization. Despite a high gross margin of 70.3% and solid operating ma…
Accumulation Zones
Metric ASML PFE
Zone Low $1,586.63 $25.39
Zone High $1,798.18 $28.77
In Buy Zone? Yes Yes
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