ASML vs MRK: Which Is the Better Buy?

Side-by-side comparison of ASML Holding N.V. and Merck & Co., Inc. โ€” fair value, conviction, valuation metrics, and QuantHub research signals. Updated 2026-09-24.
ASML Holding N.V. ยท Technology
$1,744.61
-0.7% upside to fair value
Med Conviction Grade C High Quality
VS
Merck & Co., Inc. ยท Healthcare
$147.17
-4.1% upside to fair value
Med Conviction Grade C
QuantHub Verdict
ASML has more upside to fair value (-0.7%). These are model outputs โ€” not personalized investment advice. See all research โ†’
Valuation & Fundamentals
Metric ASML MRK
Current Price $1,744.61 $147.17
Fair Value Estimate $1,732.49 $141.07
Upside to Fair Value -0.7% -4.1%
Market Cap $672.4B $363.5B
Forward P/E โ€” โ€”
EV / EBITDA 42.0x 29.6x
Price / Sales 19.0x 5.5x
Price / FCF 67.2x 22.6x
Revenue Growth YoY +21.3% +5.1%
Gross Margin 52.7% 75.4%
Operating Margin 35.4% 16.7%
Return on Equity 52.4% 6.6%
Dividend Yield 0.51% 2.31%
FCF Yield 1.49% 4.42%
Analyst Consensus Buy Buy
Investment Thesis
ASML โ€” ASML Holding N.V.
ASML Holding N.V. is the Dutch semiconductor equipment maker that supplies lithography, metrology, and inspection systems, including the extreme ultraviolet (EUV) machines required to pattern the most advanced logic and memory chips, and it holds what current coverage describes as a near-monopoly on those EUV tools. The business quality is genuinely high: TTM gross margin of 52.7%, TTM operating โ€ฆ
MRK โ€” Merck & Co., Inc.
Merck & Co., Inc. is a global healthcare leader with two core divisions, Pharmaceuticals and Animal Health, spanning oncology, vaccines, acute hospital care, immunology, neuroscience, virology, cardiovascular and diabetes, and it employs roughly 74,000 people under CEO Robert Davis. The business quality is medium: TTM gross margin of 75.4% and TTM operating margin of 16.7% reflect a genuinely higโ€ฆ
Accumulation Zones
Metric ASML MRK
Zone Low $1,299.37 $105.80
Zone High $1,472.62 $119.91
In Buy Zone? No No
โ† ASML Research    MRK Research โ†’    All Research