ASML vs LLY: Which Is the Better Buy?
Side-by-side comparison of ASML Holding N.V. and Eli Lilly and Company β fair value, conviction, valuation metrics, and QuantHub research signals.
Updated 2026-04-22.
ASML Holding N.V. Β· Technology
$1,458.97
+65.1% upside to fair value
Grade B
High Quality
VS
Eli Lilly and Company Β· Healthcare
$939.47
+71.1% upside to fair value
High Conviction
Grade A
QuantHub Verdict
LLY has more upside to fair value
(+71.1%).
LLY trades at a lower forward P/E
(27.4x).
These are model outputs β not personalized investment advice.
See all research β
Valuation & Fundamentals
| Metric |
ASML |
LLY |
| Current Price |
$1,458.97 |
$939.47 |
| Fair Value Estimate |
$2,408.73 |
$1,607.00 |
| Upside to Fair Value |
+65.1%
|
+71.1%
|
| Market Cap |
$562.3B |
$887.6B |
| Forward P/E |
48.3x
|
27.4x
|
| EV / EBITDA |
37.6x
|
35.8x
|
| Price / Sales |
14.4x
|
14.8x
|
| Price / FCF |
54.4x
|
107.6x
|
| Revenue Growth YoY |
+13.2%
|
+44.7%
|
| Gross Margin |
52.6%
|
83.8%
|
| Operating Margin |
34.8%
|
45.6%
|
| Return on Equity |
52.0%
|
77.8%
|
| Dividend Yield |
0% |
0.56% |
| FCF Yield |
1.84%
|
0.93%
|
| Analyst Consensus |
Strong Buy
|
Strong Buy
|
Investment Thesis
ASML Holding N.V. is a leading technology company specializing in semiconductor manufacturing equipment, particularly extreme ultraviolet lithography machines which hold a near-monopoly position. The company benefits from a durable competitive moat driven by its technological leadership, high barriers to entry, and strong demand from semiconductor manufacturers globally, especially in China. Despβ¦
Eli Lilly remains the dominant GLP-1 franchise holder with Mounjaro and Zepbound generating $36.5B combined in 2025 on 45% total revenue growth to $65.2B. The company guided $80-83B for 2026, well above prior Street consensus, and launched Foundayo (oral GLP-1, FDA approved April 2026) with $1.5B pre-built inventory. At $939 the stock trades at 14.8x P/S, right at its 5-year median, and 27.4x forβ¦
Accumulation Zones
| Metric |
ASML |
LLY |
| Zone Low |
$1,806.55 |
$1,205.00 |
| Zone High |
$2,047.42 |
$1,366.00 |
| In Buy Zone? |
Yes
|
Yes
|