AMZN vs ISRG: Which Is the Better Buy?

Side-by-side comparison of Amazon.com, Inc. and Intuitive Surgical, Inc. — fair value, conviction, valuation metrics, and QuantHub research signals. Updated 2026-04-22.
Amazon.com, Inc. · Consumer Cyclical
$250.56
+32.0% upside to fair value
Grade B High Quality
VS
Intuitive Surgical, Inc. · Healthcare
$451.29
+130.4% upside to fair value
Grade B High Quality
QuantHub Verdict
ISRG has more upside to fair value (+130.4%). AMZN trades at a lower forward P/E (34.5x). These are model outputs — not personalized investment advice. See all research →
Valuation & Fundamentals
Metric AMZN ISRG
Current Price $250.56 $451.29
Fair Value Estimate $330.77 $1,039.74
Upside to Fair Value +32.0% +130.4%
Market Cap $2,689.7B $160.3B
Forward P/E 34.5x 53.8x
EV / EBITDA 16.7x 40.5x
Price / Sales 3.8x 15.2x
Price / FCF 349.5x 64.3x
Revenue Growth YoY +13.6% +23.0%
Gross Margin 50.3% 66.3%
Operating Margin 11.2% 30.5%
Return on Equity 21.9% 17.0%
Dividend Yield 0% 0%
FCF Yield 0.29% 1.55%
Analyst Consensus Strong Buy Strong Buy
Investment Thesis
AMZN — Amazon.com, Inc.
Amazon.com, Inc. operates as a global leader in e-commerce and cloud computing, generating $716.9 billion in net sales for fiscal 2025 with a strong presence in North America, International markets, and AWS. The company benefits from durable competitive moats in e-commerce, where it is America’s largest online retailer with over four times the sales of its nearest rival as of 2015, and in cloud c…
ISRG — Intuitive Surgical, Inc.
Intuitive Surgical, Inc. is a leading healthcare company specializing in robotic-assisted surgery through its flagship da Vinci system, which has established a durable competitive moat with approximately 10,000 systems installed globally and nearly 17 million procedures performed by the end of 2024. The company benefits from a high-quality business model characterized by 85% recurring revenue, st…
Accumulation Zones
Metric AMZN ISRG
Zone Low $248.08 $779.81
Zone High $281.15 $883.78
In Buy Zone? Yes Yes
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