AMZN vs ISRG: Which Is the Better Buy?

Side-by-side comparison of Amazon.com, Inc. and Intuitive Surgical, Inc. โ€” fair value, conviction, valuation metrics, and QuantHub research signals. Updated 2026-09-25.
Amazon.com, Inc. ยท Consumer Cyclical
$251.19
+18.5% upside to fair value
Med Conviction Grade B High Quality
VS
Intuitive Surgical, Inc. ยท Healthcare
$399.52
+22.4% upside to fair value
Med Conviction Grade B High Quality
QuantHub Verdict
ISRG has more upside to fair value (+22.4%). These are model outputs โ€” not personalized investment advice. See all research โ†’
Valuation & Fundamentals
Metric AMZN ISRG
Current Price $251.19 $399.52
Fair Value Estimate $297.67 $488.97
Upside to Fair Value +18.5% +22.4%
Market Cap $2,702.1B $141.1B
Forward P/E โ€” โ€”
EV / EBITDA 11.2x 30.7x
Price / Sales 3.5x 12.8x
Price / FCF โ€” 44.0x
Revenue Growth YoY +19.6% +18.5%
Gross Margin 50.8% 66.7%
Operating Margin 12.1% 31.3%
Return on Equity 30.5% 17.8%
Dividend Yield 0% 0%
FCF Yield โ€” 2.28%
Analyst Consensus Strong Buy Strong Buy
Investment Thesis
AMZN โ€” Amazon.com, Inc.
Amazon.com operates a vast global retail enterprise spanning online and physical stores, third-party seller services, advertising, subscription offerings, and Amazon Web Services, the world's largest cloud infrastructure provider. The business quality is high: trailing-twelve-month gross margin of 50.8%, operating margin of 12.1%, and net margin of 17.4% reflect a durable mix shift toward high-maโ€ฆ
ISRG โ€” Intuitive Surgical, Inc.
Intuitive Surgical develops, produces, and commercializes the da Vinci surgical system and the Ion endoluminal system, along with instruments, accessories, training, and digital solutions that drive a large installed-base and recurring-revenue model. Business quality is high: TTM gross margin of 66.7%, operating margin of 31.3%, net margin of 28.4%, ROE of 17.8%, and revenue growth of 18.5% with โ€ฆ
Accumulation Zones
Metric AMZN ISRG
Zone Low $223.25 $366.73
Zone High $253.02 $415.62
In Buy Zone? Yes Yes
โ† AMZN Research    ISRG Research โ†’    All Research