AMD vs ISRG: Which Is the Better Buy?

Side-by-side comparison of Advanced Micro Devices, Inc. and Intuitive Surgical, Inc. β€” fair value, conviction, valuation metrics, and QuantHub research signals. Updated 2026-09-25.
Advanced Micro Devices, Inc. Β· Technology
$614.61
-13.7% upside to fair value
Med Conviction Grade C
VS
Intuitive Surgical, Inc. Β· Healthcare
$399.52
+22.4% upside to fair value
Med Conviction Grade B High Quality
QuantHub Verdict
ISRG has more upside to fair value (+22.4%). These are model outputs β€” not personalized investment advice. See all research β†’
Valuation & Fundamentals
Metric AMD ISRG
Current Price $614.61 $399.52
Fair Value Estimate $530.25 $488.97
Upside to Fair Value -13.7% +22.4%
Market Cap $1,002.2B $141.1B
Forward P/E β€” β€”
EV / EBITDA 93.4x 30.7x
Price / Sales 24.3x 12.8x
Price / FCF 119.3x 44.0x
Revenue Growth YoY +50.1% +18.5%
Gross Margin 53.2% 66.7%
Operating Margin 15.7% 31.3%
Return on Equity 10.1% 17.8%
Dividend Yield 0% 0%
FCF Yield 0.84% 2.28%
Analyst Consensus Strong Buy Strong Buy
Investment Thesis
AMD β€” Advanced Micro Devices, Inc.
Advanced Micro Devices designs x86 CPUs, GPUs, and data-center accelerators across two segments, Computing and Graphics and Enterprise, Embedded and Semi-Custom, with 31,000 employees and a $1.002 trillion market capitalization at $614.61 per share. The business quality is genuinely improving: revenue grew 50.1% year over year in the most recent quarter, earnings grew 163.4% year over year in the…
ISRG β€” Intuitive Surgical, Inc.
Intuitive Surgical develops, produces, and commercializes the da Vinci surgical system and the Ion endoluminal system, along with instruments, accessories, training, and digital solutions that drive a large installed-base and recurring-revenue model. Business quality is high: TTM gross margin of 66.7%, operating margin of 31.3%, net margin of 28.4%, ROE of 17.8%, and revenue growth of 18.5% with …
Accumulation Zones
Metric AMD ISRG
Zone Low $397.69 $366.73
Zone High $450.71 $415.62
In Buy Zone? No Yes
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