AMD vs ISRG: Which Is the Better Buy?

Side-by-side comparison of Advanced Micro Devices, Inc. and Intuitive Surgical, Inc. β€” fair value, conviction, valuation metrics, and QuantHub research signals. Updated 2026-05-05.
Advanced Micro Devices, Inc. Β· Technology
$341.54
+38.2% upside to fair value
Grade C High Quality
VS
Intuitive Surgical, Inc. Β· Healthcare
$451.29
+45.0% upside to fair value
Grade B High Quality
QuantHub Verdict
ISRG has more upside to fair value (+45.0%). ISRG trades at a lower forward P/E (53.8x). These are model outputs β€” not personalized investment advice. See all research β†’
Valuation & Fundamentals
Metric AMD ISRG
Current Price $341.54 $451.29
Fair Value Estimate $472.05 $654.37
Upside to Fair Value +38.2% +45.0%
Market Cap $556.9B $160.3B
Forward P/E 128.4x 53.8x
EV / EBITDA 76.3x 40.5x
Price / Sales 16.1x 15.2x
Price / FCF 82.7x 64.3x
Revenue Growth YoY +34.1% +23.0%
Gross Margin 49.5% 66.3%
Operating Margin 10.7% 30.5%
Return on Equity 7.2% 17.0%
Dividend Yield 0% 0%
FCF Yield 1.21% 1.55%
Analyst Consensus Buy Strong Buy
Investment Thesis
AMD β€” Advanced Micro Devices, Inc.
Advanced Micro Devices, Inc. is a leading semiconductor company specializing in high-performance computing products including CPUs and GPUs, with a strong foothold in data center, client, gaming, and embedded markets. The company benefits from a durable competitive moat driven by its technology leadership in Zen/Ryzen CPUs and graphics processors, as well as strategic diversification through the …
ISRG β€” Intuitive Surgical, Inc.
Intuitive Surgical, Inc. is a leading healthcare company specializing in robotic-assisted surgery through its flagship da Vinci system, which has established a durable competitive moat with approximately 10,000 systems installed globally and nearly 17 million procedures performed by the end of 2024. The company benefits from a high-quality business model characterized by 85% recurring revenue, st…
Accumulation Zones
Metric AMD ISRG
Zone Low $354.04 $490.78
Zone High $401.24 $556.21
In Buy Zone? Yes Yes
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