AMAT vs TMO: Which Is the Better Buy?

Side-by-side comparison of Applied Materials, Inc. and Thermo Fisher Scientific Inc. β€” fair value, conviction, valuation metrics, and QuantHub research signals. Updated 2026-06-20.
Applied Materials, Inc. Β· Technology
$617.11
-45.0% upside to fair value
Grade C High Quality
VS
Thermo Fisher Scientific Inc. Β· Healthcare
$464.61
+7.2% upside to fair value
Grade A High Quality
QuantHub Verdict
TMO has more upside to fair value (+7.2%). TMO trades at a lower forward P/E (25.2x). These are model outputs β€” not personalized investment advice. See all research β†’
Valuation & Fundamentals
Metric AMAT TMO
Current Price $617.11 $464.61
Fair Value Estimate $339.41 $498.27
Upside to Fair Value -45.0% +7.2%
Market Cap $490.0B $172.7B
Forward P/E 57.7x 25.2x
EV / EBITDA 44.0x 19.1x
Price / Sales 16.9x 3.8x
Price / FCF 82.1x 25.6x
Revenue Growth YoY +11.4% +6.2%
Gross Margin 49.0% 39.4%
Operating Margin 29.5% 17.8%
Return on Equity 39.8% 13.3%
Dividend Yield 0% 0%
FCF Yield 1.22% 3.91%
Analyst Consensus Strong Buy Strong Buy
Investment Thesis
AMAT β€” Applied Materials, Inc.
Applied Materials, Inc. is a leading semiconductor equipment manufacturer specializing in wafer fabrication equipment and services, with a strong competitive moat in deposition, etch, implant, and services segments. Led by CEO Gary Dickerson with over 12 years at the helm, the company has demonstrated durable earnings growth and a robust patent portfolio. Despite solid revenue growth of 11.4% and…
TMO β€” Thermo Fisher Scientific Inc.
Thermo Fisher Scientific is a leading healthcare company specializing in life science tools, diagnostics, and contract research and manufacturing services. It operates with a broad, multi-layered moat driven by scale, integration, and a long-tenured management team. The company exhibits solid fundamentals with a 13.3% ROE, 6.2% revenue growth, and 9.6% earnings growth in the most recent quarter. …
Accumulation Zones
Metric AMAT TMO
Zone Low $254.56 $373.70
Zone High $288.50 $423.53
In Buy Zone? No No
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