AMAT vs TMO: Which Is the Better Buy?

Side-by-side comparison of Applied Materials, Inc. and Thermo Fisher Scientific Inc. — fair value, conviction, valuation metrics, and QuantHub research signals. Updated 2026-07-06.
Applied Materials, Inc. · Technology
$603.04
-45.0% upside to fair value
Grade C High Quality
VS
Thermo Fisher Scientific Inc. · Healthcare
$464.61
+7.2% upside to fair value
Grade A High Quality
QuantHub Verdict
TMO has more upside to fair value (+7.2%). TMO trades at a lower forward P/E (25.2x). These are model outputs — not personalized investment advice. See all research →
Valuation & Fundamentals
Metric AMAT TMO
Current Price $603.04 $464.61
Fair Value Estimate $331.67 $498.27
Upside to Fair Value -45.0% +7.2%
Market Cap $478.8B $172.7B
Forward P/E 56.4x 25.2x
EV / EBITDA 43.0x 19.1x
Price / Sales 16.5x 3.8x
Price / FCF 80.3x 25.6x
Revenue Growth YoY +11.4% +6.2%
Gross Margin 49.0% 39.4%
Operating Margin 29.5% 17.8%
Return on Equity 39.8% 13.3%
Dividend Yield 0% 0%
FCF Yield 1.25% 3.91%
Analyst Consensus Strong Buy Strong Buy
Investment Thesis
AMAT — Applied Materials, Inc.
Applied Materials, Inc. is a leading semiconductor equipment company with a strong competitive moat in multiple wafer fab equipment segments, driven by its scale, infrastructure, and technology leadership in AI-critical process steps. The company benefits from a seasoned management team led by CEO Gary Dickerson, who has over 12 years at the helm and a track record of strong revenue and profitabi…
TMO — Thermo Fisher Scientific Inc.
Thermo Fisher Scientific is a leading healthcare company specializing in life science tools, diagnostics, and contract research and manufacturing services. It operates with a broad, multi-layered moat driven by scale, integration, and a long-tenured management team. The company exhibits solid fundamentals with a 13.3% ROE, 6.2% revenue growth, and 9.6% earnings growth in the most recent quarter. …
Accumulation Zones
Metric AMAT TMO
Zone Low $248.75 $373.70
Zone High $281.92 $423.53
In Buy Zone? No No
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