AMAT vs ISRG: Which Is the Better Buy?

Side-by-side comparison of Applied Materials, Inc. and Intuitive Surgical, Inc. — fair value, conviction, valuation metrics, and QuantHub research signals. Updated 2026-07-16.
Applied Materials, Inc. · Technology
$603.04
-45.0% upside to fair value
Grade C High Quality
VS
Intuitive Surgical, Inc. · Healthcare
$388.97
+45.0% upside to fair value
Grade B High Quality
QuantHub Verdict
ISRG has more upside to fair value (+45.0%). ISRG trades at a lower forward P/E (46.5x). These are model outputs — not personalized investment advice. See all research →
Valuation & Fundamentals
Metric AMAT ISRG
Current Price $603.04 $388.97
Fair Value Estimate $331.67 $564.01
Upside to Fair Value -45.0% +45.0%
Market Cap $478.8B $137.8B
Forward P/E 56.4x 46.5x
EV / EBITDA 43.0x 31.4x
Price / Sales 16.5x 13.0x
Price / FCF 80.3x 48.6x
Revenue Growth YoY +11.4% +23.0%
Gross Margin 49.0% 66.3%
Operating Margin 29.5% 30.5%
Return on Equity 39.8% 17.0%
Dividend Yield 0% 0%
FCF Yield 1.25% 2.06%
Analyst Consensus Strong Buy Strong Buy
Investment Thesis
AMAT — Applied Materials, Inc.
Applied Materials, Inc. is a leading semiconductor equipment company with a strong competitive moat in multiple wafer fab equipment segments, driven by its scale, infrastructure, and technology leadership in AI-critical process steps. The company benefits from a seasoned management team led by CEO Gary Dickerson, who has over 12 years at the helm and a track record of strong revenue and profitabi…
ISRG — Intuitive Surgical, Inc.
Intuitive Surgical, Inc. operates in the healthcare sector, specializing in medical devices with a strong focus on robotic-assisted surgery systems. The company demonstrates high business quality with a durable competitive moat supported by a 17.0% return on equity, robust gross margin of 66.3%, and solid operating margin of 30.5%. Revenue and earnings growth in the most recent quarter were impre…
Accumulation Zones
Metric AMAT ISRG
Zone Low $248.75 $423.01
Zone High $281.92 $479.41
In Buy Zone? No Yes
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