ABBV vs HD: Which Is the Better Buy?
Side-by-side comparison of AbbVie Inc. and The Home Depot, Inc. — fair value, conviction, valuation metrics, and QuantHub research signals.
Updated 2026-04-11.
AbbVie Inc. · Healthcare
$208.05
+4.5% upside to fair value
Grade C
High Quality
VS
The Home Depot, Inc. · Consumer Cyclical
$337.34
+12.1% upside to fair value
Med Conviction
Grade B
QuantHub Verdict
HD has more upside to fair value
(+12.1%).
ABBV trades at a lower forward P/E
(14.9x).
These are model outputs — not personalized investment advice.
See all research →
Valuation & Fundamentals
| Metric |
ABBV |
HD |
| Current Price |
$208.05 |
$337.34 |
| Fair Value Estimate |
$217.50 |
$378.00 |
| Upside to Fair Value |
+4.5%
|
+12.1%
|
| Market Cap |
$367.9B |
$336.0B |
| Forward P/E |
14.9x
|
23.0x
|
| EV / EBITDA |
16.7x
|
18.1x
|
| Price / Sales |
6.1x
|
2.3x
|
| Price / FCF |
20.9x
|
29.7x
|
| Revenue Growth YoY |
+8.6%
|
+3.2%
|
| Gross Margin |
83.7%
|
33.3%
|
| Operating Margin |
34.7%
|
12.7%
|
| Return on Equity |
-129.24%
|
110.5%
|
| Dividend Yield |
3.2% |
2.44% |
| FCF Yield |
4.78%
|
3.37%
|
| Analyst Consensus |
Buy
|
Buy
|
Investment Thesis
AbbVie is a leading diversified biopharmaceutical company navigating the post-Humira transition with strong momentum from Skyrizi and Rinvoq in immunology and continued growth in neuroscience. Full-year 2025 revenue reached $61.2 billion with a gross margin of 83.7% and operating margin of 34.7%, demonstrating operational strength despite the ongoing Humira erosion. Management guides to $67 billi…
Home Depot remains the world's largest home improvement retailer with 2,350+ stores, dominant 52% market share, and a rapidly growing Pro contractor segment bolstered by the SRS Distribution acquisition. The stock has declined 21% from its $427 high to $337, but now trades at 2.28x P/S, near the 5-year median of 2.31x, and 26.5x P/E which is above the 5-year median of 23.5x. EPS declined 4.6% in …
Accumulation Zones
| Metric |
ABBV |
HD |
| Zone Low |
$163.13 |
$285.00 |
| Zone High |
$184.88 |
$320.00 |
| In Buy Zone? |
No
|
No
|